Proven to Work Supplements for Depression

Depression Suppplements

Here we’ll be discussing some supplements for depression, supplements that have the potential to alleviate some depressive symptoms, to an extent, when it comes to overcoming depression.

St. John’s Wort

This is a common recommendation as a supplement for depression. There are some studies suggesting it may be helpful if you’ve been feeling depressed. There are also some studies suggesting it does nothing. The results are not conclusive. If you are taking an anti-depressant, do not take this in addition to it. That could cause a dangerous condition known as serotonin syndrome. 

The recommended dosage is 900mg in 2-3 divided dosages, so 450 twice a day or 300mg three times a day.

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 Rhodiola Rosea 

According to some research, Rhodiola Rosea may be effective in treating stress, fatigue, and depression. It is an adaptogen. This is the brand I recommend for this product. The recommended dosage is approximately 400mg-600mg, split into two doses.

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Saffron has been found to be a helpful treatment for depression for those with mild depression. Although it still is a treatment for depression for other forms of depression, sub-clinical depression is where it shines. The only one I have found that matches the dosages used in the studies is this one. The recommended dosage is 30mg-60mg per day.

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Fish Oil

Although it’s still in its early stages, research is promising that fish oil can help to overcome depression. Fish oil consists of EPA and DHA, and it’s primarily the EPA that has an effect on depression. Therefore, a supplement should be higher in EPA than DHA, like in this one. The recommended dosage is approximately 900 EPA and 600 DHA.

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´╗┐NAC (N-acetylcysteine)

Strong evidence suggests that NAC may be a treatment for depression.

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The recommended dosage is 2g/day. That may be more easily achieved with the powder: 

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Vitamin D

Vitamin D is certainly a depression treatment but not in all people. It’s not a guarantee that it’s how to feel better, but if you were to get a large enough group together, it would be a guarantee that it would raise some of their moods. Either way, it’s healthy to get enough vitamin D. Many people don’t get enough. So even if it unfortunately doesn’t improve your depressive symptoms, let it improve your health. Here’s a perfectly acceptable option. The recommended dosage is at least 2,000 IUs. 

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 B Vitamins

It’s quite nearly proven that B vitamins improve depressive symptoms because B vitamins are directly involved in mood. The recommended dosages are at least 50mg of B6, at least 400mcg of Folate, and at least 500mg of B12. This one is not bad:

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This is more like an anti-depressant. This is something already found in our bodies. Taking it as a supplement is mildly energizing and mildly mood-boosting. You can take it up to four times a day. 

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This seems to take a while to make you feel better, helping you gradually overcome depression. Ginseng has been shown in many studies to improve mood, among other things. Its effect on depression is gradually becoming clearer. The recommended dosage is anywhere from 100mg to 800mg. Always start low and then go up.

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This is a synthetic derivative of thiamine (vitamin b1). It increases alertness levels, mood, and reduces anxiety. It can be purchased both as a powder and as capsules. This could be part of a plan on how to feel better. Here is a link to the capsules. A dosage of up to 600mg is okay. 

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These will quickly make you feel better, as you may know, but they won’t necessarily be overcoming depression. As the public seems to understand, coffee, tea, and caffeine provide boosts. The reason “caffeine” is separate is because you can buy caffeine separately, in the form of capsules, powder, gummies, etc. Coffee and Tea, though, contain more than just caffeine and so will provide more benefits than caffeine alone, but they all have their place. I won’t be linking to any of them. I just wanted to mention them. This, too, could be part of a plan on how to feel better. 

Lithium Orotate

This is a great supplement to overcome depression with. You may recognize the word “lithium.” The lithium prescribed by doctors is lithium carbonate, a different form of it. Lithium orotate can be bought OTC. It’s shown to provide many benefits, one of those being a reduction in depressive symptoms. You would start at its lowest dose, and if that is not effective within a couple weeks, you would go to the next dose up. The highest dose you would try is 20mg. Here’s a link to the lowest dosage: 

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This is an indirect supplement for depression, working on how to feel better. This is an amino acid which may provide a mood and energy boost. You can safely take it in high doses, but, as always, start with the lowest dose to assess for tolerance. You can get it as a powder to put into a drink, or you can get it as a capsule. I will be linking to the capsules.

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Amino Acids

Amino acids are found in proteins and convert to the chemicals in our brain that we want, such as serotonin and dopamine.

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Noopept is a nootropic and in addition to its purported cognitive benefits, it may also improve mood and reduce anxiety. You would take 10mg at a time, up to a maximum of 30mg a day.

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Multiple Ingredients

Here is a supplement that’s four supplements in one. It contains lithium orotate, turmeric, kanna, and PEA. The link explains most of these ingredients but all four are useful. It might seem expensive, but if you were to buy the four supplements separately it would cost more.

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